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Acuros® advanced dose calculation algorithm
Acuros is Transpire's next generation radiotherapy dose calculation software, which is distributed by Varian Medical Systems ( www.varian.com) as an integral part of the Eclipse TM treatment planning system. Through the novel application of leading edge numerical methods, Acuros provides an unprecedented combination of speed, accuracy, and precision; advancing the state-of-the-art in radiotherapy planning and improving overall quality of care.
Unlike correction and model-based methods, Acuros calculates dose by directly solving the governing transport equations. Acuros accurately accounts for all relevant neutral and charged particle interactions, without the use of pre-calculated kernels or empirical corrections. Since Acuros and Monte Carlo solve the same equations through different methods (Acuros-deterministically, Monte Carlo-stochastically), the achievable accuracy of both methods are comparable.
Acuros combines the accuracy of Monte Carlo with the speed of approximate methods. Acuros is free of statistical noise, enabling the effects of small treatment planning perturbations to be accurately and rapidly assessed.
Selected Publications:
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O. Vassiliev, T. Wareing, J. McGhee, G. Failla, M. Salehpour, F. Mourtada, ‘Validation of a new grid-based Boltzmann equation solver for dose calculation in radiotherapy with photon beams’, Phys. Med. Biol. (55) 581-598, 2010. |
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K. Zourari, E. Pantelis, A. Moutsatsos, L. Petrokokkinos, P. Karaiskos, L. Sakelliou, E. Georgiou, P. Papagiannis, ‘Dosimetric accuracy of a deterministic radiation transport based 192lr brachytherapy treatment planning system. Part 1: single sources and bounded homogeneous geometries’, Med Phys. 2010 Feb;37(2):649-661. |
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A. Fogliata, G. Nicolini, A. Clivio, E. Vanetti, P. Mancosu, L. Cozzi, 'Dosimetric validation of the Acuros XB Advanced Dose Calculation algorithm: fundamental characterization in water', Phys. Med. Biol. (56) 1879-1904, 2011. |
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K. Bush, I. M. Gagne, S. Zavgorodni, W. Ansbacher, and W. Beckham, 'Dosimetric validation of Acuros(r) XB with Monte Carlo methods for photon dose calculations', Med. Phys. 38, 2208 (2011); |
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A. Fogliata, G. Nicolini, A. Clivio, E. Vanetti, L. Cozzi, 'Dosimetric evaluation of Acuros XB Advanded Dose Calculation algorithm in heterogeneous media', Radiat Oncol. 2011 Jul 19;6(1):82. |
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T. Han, JK Mikell, M. Salehpour, F. Mourtada, 'Dosimetric comparison of Acuros XB deterministic radiation transport method with Monte Carlo and model-based convolution methods in heterogeneous media.', Med Phys. 2011 May;38(5):2651-64. |
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A. Fogliata, G. Nicolini, A. Clivio, E. Vanetti, L. Cozzi, 'On the dosimetric impact of inhomogeneity management in the Acuros XB algorithm for breast treatment', Radiat Oncol. 2011 Aug 26;6:103. |
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A. Fogliata, G. Nicolini, A. Clivio, E. Vanetti, L. Cozzi, 'Accuracy of AcurosXB and AAA dose calculation for small fields with reference to RapidArc stereotactic treatments', Med Phys. 2011 Nov;38(11):6228. |
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Hoffmann L, Jorgensen MB, Muren LP, Peterson JB, 'Clinical validation of the Acuros XB photon dose calculation algorithm, a grid-based Boltzmann equation solver', Acta Oncol 2011 Nov. 7. |
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